Lee Enfield Lockwood was born February 17, 1946 in Cumberland, Maryland, to Sarah and Sam Enfield. She grew up in Houston, Texas, attending a local public elementary school and a private high school. She attended Duke University and majored in political science, graduating in 1968. She moved to Washington, D.C. and was hired by the staff of Senator Muskie. She worked for Muskie from 1969 to 1978, beginning with tasks like sorting and reading the mail and eventually handling speech writing and legislation.
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Nicoll, Don, "Lockwood, Lee Enfield oral history interview" (2002). Edmund S. Muskie Oral History Collection. 225.