Event Website
http://www.bates.edu/mt-david-summit.xml
Start Date
1-4-2011 1:45 PM
End Date
1-4-2011 3:00 PM
Description
Urinary tract infections affect over 11 million women in the United States each year. While Escherichia coli accounts for over 80% of infection, Staphylococcus saprophyticus, the second most common, is known to disproportionately affect young college-aged women. Currently, Trimethoprim-sulfamethoxazole (TMP-SMX) is the recommended therapy for acute uncomplicated UTI. Increasing strains of drug resistant S. saprophyticus, however, have introduced the need to re-evaluate these first-line therapies. Many studies have shown that regular consumption of cranberry juice can help to reduce recurrent infections and may help to slow the development of antibiotic resistance, but there has been little research done specifically for S. saprophyticus. This current study explores the heteroresistance for S. saprophyticus to traditional antibiotics and compares this with the use of cranberry in preventing biofilm formation. Determining resistance profiles for strains of S. saprophyticus may help in providing more specific therapies and reduce the development of resistant strains.
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Comparing Antibiotic Resistance among Clinical Isolates of Staphylococcus saprophyticus with the Effect of Cranberry (Vaccinium macrocarpon) on Growth
Urinary tract infections affect over 11 million women in the United States each year. While Escherichia coli accounts for over 80% of infection, Staphylococcus saprophyticus, the second most common, is known to disproportionately affect young college-aged women. Currently, Trimethoprim-sulfamethoxazole (TMP-SMX) is the recommended therapy for acute uncomplicated UTI. Increasing strains of drug resistant S. saprophyticus, however, have introduced the need to re-evaluate these first-line therapies. Many studies have shown that regular consumption of cranberry juice can help to reduce recurrent infections and may help to slow the development of antibiotic resistance, but there has been little research done specifically for S. saprophyticus. This current study explores the heteroresistance for S. saprophyticus to traditional antibiotics and compares this with the use of cranberry in preventing biofilm formation. Determining resistance profiles for strains of S. saprophyticus may help in providing more specific therapies and reduce the development of resistant strains.
http://scarab.bates.edu/mt_david_summit/MDS2011/02Poster/15